Hormone recept pos w hmn epdrml grth fctr recept 2 neg stat

Hormone receptor positive with human epidermal growth factor receptor 2 negative status

📋Clinical Description

This code identifies breast cancer that tests positive for estrogen and/or progesterone receptors but negative for human epidermal growth factor receptor 2 (HER2). This specific molecular profile is crucial for determining appropriate targeted therapies and prognosis.

🎯When to Use

Use this code for patients with a confirmed diagnosis of breast cancer where immunohistochemistry (IHC) or FISH testing results indicate hormone receptor positivity (ER+ and/or PR+) and HER2 negativity. This status is typically determined from biopsy or surgical pathology reports.

💡Coding Tips

Always confirm the hormone receptor and HER2 status from the pathology report.
This code is an add-on code used in conjunction with a primary breast cancer diagnosis (e.g., C50.x).
Ensure the documentation clearly distinguishes between ER, PR, and HER2 status.

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Clinical Notes

Inclusion Terms

HR+ with HER2-

Code Hierarchy

▲Z17.41Hormone receptor positive

Z17.411(current)

Same Category

Z17Estrogen, and other hormones and factors receptor status Z17.0Estrogen receptor positive status [ER+]Z17.1Estrogen receptor negative status [ER-]Z17.2Progesterone receptor status Z17.21Progesterone receptor positive status Z17.22Progesterone receptor negative status Z17.3