Genetic susceptibility to malignant neoplasm of endometrium

This code signifies an inherited predisposition or increased genetic risk for developing endometrial cancer. It indicates that a patient possesses specific genetic markers or a family history that significantly elevates their likelihood of developing this type of malignant neoplasm.

This code is appropriate for patients identified through genetic testing as carriers of mutations associated with increased endometrial cancer risk (e.g., Lynch syndrome). It should also be used when a strong family history of endometrial cancer, suggestive of a hereditary syndrome, prompts increased surveillance or prophylactic measures.

• Assign this code as a secondary diagnosis when the patient is being managed for their genetic risk, but no active malignancy is present.
• Do not use this code if the patient already has a confirmed diagnosis of endometrial cancer; instead, code the specific malignancy.
• Consider co-reporting with codes for genetic counseling (Z31.5) or prophylactic interventions if applicable.