T45.3X6A
ICD-10-CMThis code signifies a patient experiencing adverse effects due to receiving an insufficient amount of prescribed enzymes. This underdosing can lead to a worsening of the underlying condition for which the enzymes were prescribed, as the body is not receiving adequate enzymatic support.
This code is appropriate for documenting the initial presentation of symptoms or complications directly attributable to a patient not receiving enough of their prescribed enzyme medication. Examples include pancreatic enzyme replacement therapy (PERT) underdosing in cystic fibrosis patients leading to malabsorption, or underdosing of enzyme replacement therapy for lysosomal storage disorders.
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