Abn lev drug/meds/biol subst in specimens from oth org/tiss

This code signifies the presence of an abnormal concentration of a drug, medicament, or biological substance in a non-blood or non-urine specimen, such as tissue biopsies, cerebrospinal fluid, or synovial fluid. It indicates a finding outside the expected therapeutic or normal range, suggesting potential toxicity, inadequate dosing, or unusual distribution.

Use this code when laboratory results from specimens other than blood or urine reveal an abnormal level of a specified substance. This often occurs in toxicology screenings, therapeutic drug monitoring in specific body compartments, or investigations into localized drug effects. Documentation must clearly state the substance, the abnormal level, and the specimen source.

• Do not use for abnormal drug levels found in blood (R78.-) or urine (R82.5).
• Requires specific documentation of the substance, the abnormal level, and the "other" specimen type (e.g., tissue, CSF).
• Sequence as a secondary diagnosis when the primary reason for the encounter is the condition causing the abnormal level or the adverse effect of the substance.