Balanced translocation and insertion in normal individual

This code signifies a chromosomal rearrangement where segments of chromosomes have been exchanged (balanced translocation) or added into another chromosome (insertion) without any net loss or gain of genetic material. Crucially, the individual carrying this rearrangement is phenotypically normal, meaning they do not exhibit any clinical signs or symptoms related to the chromosomal change.

Use this code for individuals identified through genetic testing, often due to recurrent miscarriages, infertility, or a family history of chromosomal abnormalities, who are found to have a balanced translocation or insertion but are otherwise healthy. Documentation should clearly state the presence of a balanced chromosomal rearrangement and the absence of associated clinical manifestations in the patient.

• Do not use this code if the individual exhibits any phenotypic abnormalities or genetic disorders related to the chromosomal rearrangement; instead, a more specific code for the resulting condition should be used.
• This code is typically used for the carrier state, not for affected offspring.
• Ensure genetic testing reports explicitly confirm a "balanced" rearrangement and "normal phenotype."