Neonatal jaundice from unspecified hepatocellular damage

This code signifies jaundice in a newborn due to liver cell damage where the specific cause of the damage is not identified. It indicates a hepatic etiology for the hyperbilirubinemia, rather than pre-hepatic or post-hepatic causes.

Use this code when a neonate presents with jaundice and diagnostic workup points to hepatocellular injury as the underlying mechanism, but the precise cause (e.g., infection, metabolic disorder, genetic defect) remains undetermined. Documentation should clearly state "neonatal jaundice due to unspecified hepatocellular damage" or similar phrasing.

• Do not use if a more specific cause of hepatocellular damage is known (e.g., P59.21 for neonatal jaundice from infection).
• Ensure documentation differentiates between conjugated and unconjugated hyperbilirubinemia, as hepatocellular damage typically leads to conjugated hyperbilirubinemia.
• Consider sequencing this code after codes for any associated symptoms or findings, if applicable, and if the hepatocellular damage is not the definitive diagnosis.