Interstitial emphysema originating in the perinatal period

This code represents the presence of air within the interstitial tissues of the lung, outside of the normal airspaces, that developed during the perinatal period (from 22 weeks gestation through 28 days after birth). This condition is often a complication of respiratory distress in newborns, particularly those requiring mechanical ventilation.

Use this code for newborns diagnosed with interstitial emphysema that originated around the time of birth. Documentation should clearly indicate the presence of air in the lung interstitium, typically confirmed by imaging studies such as chest X-rays, and specify its perinatal onset.

• Distinguish from other forms of air leak syndromes in neonates, such as pneumothorax or pneumomediastinum, unless they coexist.
• Always sequence this code after the primary condition necessitating respiratory support, such as respiratory distress syndrome (P22.0).
• Ensure documentation specifies "interstitial" emphysema to differentiate from other types of emphysema.