Newborn affected by fetal inflammatory response syndrome

This code signifies a newborn diagnosed with fetal inflammatory response syndrome (FIRS), a systemic inflammatory state occurring in utero. FIRS is characterized by elevated inflammatory markers in fetal blood, often associated with chorioamnionitis or other intrauterine infections.

Assign this code when documentation explicitly states a diagnosis of fetal inflammatory response syndrome in a newborn. This typically occurs in cases of preterm birth, premature rupture of membranes, or maternal infection where fetal inflammatory markers (e.g., elevated C-reactive protein, interleukins) were identified.

• Ensure the documentation clearly links the newborn's condition to fetal inflammatory response syndrome, not just general neonatal sepsis.
• Code any underlying maternal conditions (e.g., chorioamnionitis) that contributed to FIRS.
• Consider sequencing this code after codes for prematurity or other significant newborn conditions, if applicable.