Intrahepatic cholestasis of pregnancy, second trimester

This code signifies a liver condition specific to pregnancy, characterized by impaired bile flow within the liver during the second trimester. It results in the accumulation of bile acids in the bloodstream, leading to symptoms such as intense itching (pruritus) without a rash.

Apply this code when a pregnant patient in her second trimester is diagnosed with intrahepatic cholestasis, confirmed by elevated serum bile acid levels and clinical symptoms like generalized pruritus. Documentation should clearly state the diagnosis and the gestational trimester.

• Ensure the documentation explicitly states "second trimester" for accurate code assignment.
• Do not confuse with other liver disorders in pregnancy, such as pre-eclampsia with HELLP syndrome, which have distinct diagnostic criteria.
• Always sequence this code as a primary diagnosis when it is the reason for the encounter, or as a secondary diagnosis if managing other pregnancy complications concurrently.