Nephrogenic diabetes insipidus

This code represents a rare kidney disorder where the renal tubules are unable to respond to antidiuretic hormone (ADH), leading to excessive urination and thirst. Unlike central diabetes insipidus, the body produces ADH, but the kidneys cannot properly concentrate urine.

Assign this code when documentation specifies a diagnosis of nephrogenic diabetes insipidus, indicating a renal tubular defect in ADH response. This diagnosis is typically supported by clinical findings of polyuria, polydipsia, and laboratory tests showing dilute urine despite normal or elevated ADH levels.

• Differentiate from central diabetes insipidus (E23.2), where the pituitary gland fails to produce ADH.
• Ensure documentation clearly states "nephrogenic" to distinguish from other forms of diabetes insipidus.
• This code is typically a primary diagnosis unless it is a manifestation of another underlying condition.