I21.A1
ICD-10-CMThis code represents a myocardial infarction (heart attack) that occurs due to an imbalance between myocardial oxygen supply and demand, rather than primary coronary artery plaque rupture. It is often secondary to another acute medical condition, such as severe anemia, tachyarrhythmias, hypotension, or respiratory failure, which stresses the heart.
Use this code when documentation clearly indicates an acute myocardial infarction resulting from an oxygen supply/demand mismatch, without evidence of primary coronary artery disease plaque instability. This typically requires a rise and/or fall in cardiac biomarkers (e.g., troponin) along with clinical evidence of ischemia in the setting of a precipitating non-coronary event.
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