Immune effor cell-associated neurotoxicity synd, grade unsp

Immune effector cell-associated neurotoxicity syndrome, grade unspecified

📋Clinical Description

This code represents a neurological toxicity that can occur following immune effector cell (IEC) therapy, such as CAR T-cell therapy. It encompasses a spectrum of neurological signs and symptoms, including encephalopathy, seizures, and motor weakness, without a specified severity grade.

🎯When to Use

Use this code when a patient develops neurotoxicity after receiving immune effector cell therapy, and the medical record documents the condition as immune effector cell-associated neurotoxicity syndrome (ICANS) but does not specify a grade. This code is appropriate when the provider explicitly diagnoses ICANS without further grading.

💡Coding Tips

Do not use this code if a specific grade of ICANS (e.g., grade 1, 2, 3, 4, 5) is documented; instead, use the more specific graded codes.
Always sequence this code after the underlying malignancy for which the IEC therapy was administered.
Ensure documentation clearly links the neurotoxicity to the IEC therapy.

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Clinical Notes

Inclusion Terms

ICANS, grade unspecified

Code Hierarchy

▲G92.0Immune effector cell-associated neurotoxicity syndrome

G92.00(current)

Same Category

G92Toxic encephalopathy G92.0Immune effector cell-associated neurotoxicity syndrome G92.01Immune effector cell-associated neurotoxicity synd, grade 1 G92.02Immune effector cell-associated neurotoxicity synd, grade 2 G92.03Immune effector cell-associated neurotoxicity synd, grade 3 G92.04Immune effector cell-associated neurotoxicity synd, grade 4