Personality change due to known physiological condition

This code represents a significant and persistent alteration in an individual's characteristic patterns of thought, emotion, and behavior that is directly attributable to a diagnosed medical condition affecting brain function. These changes often manifest as impaired impulse control, emotional lability, apathy, or disinhibition, differing markedly from the patient's premorbid personality.

Use this code when documentation clearly links a personality change to an underlying physiological cause, such as a traumatic brain injury, stroke, tumor, or neurodegenerative disease. The medical record must explicitly state the physiological condition and its causal relationship to the personality alteration.

• Ensure the documentation specifies the underlying physiological condition causing the personality change.
• Differentiate from F60.- (specific personality disorders), which are typically developmental and not directly caused by an acute physiological event.
• Review "Excludes1" notes carefully to avoid co-coding with conditions like mild cognitive impairment or postconcussional syndrome, as these are mutually exclusive.