F06.31
ICD-10-CMMood disorder due to known physiological condition with depressive features
This diagnosis code signifies a mood disturbance characterized predominantly by depressive symptoms that are directly attributable to an underlying medical condition or substance. The physiological condition is considered the primary etiology for the depressive features, rather than an independent primary mood disorder.
Apply this code when documentation clearly links depressive symptoms (e.g., anhedonia, low mood, fatigue) to a known physiological cause, such as hypothyroidism, neurological disorders, or medication side effects. The medical record must explicitly state the causal relationship between the physiological condition and the mood disturbance.
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