Plasminogen deficiency

This code represents a rare genetic disorder characterized by abnormally low levels of plasminogen, a protein essential for fibrinolysis (the breakdown of blood clots). Individuals with this deficiency are at an increased risk for developing ligneous (woody) lesions, particularly on mucous membranes, due to impaired clot degradation and excessive fibrin deposition.

Use this code when documentation confirms a diagnosis of plasminogen deficiency, often identified through laboratory testing showing reduced plasminogen activity or antigen levels. It is typically associated with conditions like ligneous conjunctivitis, ligneous gingivitis, or other ligneous lesions affecting various organ systems.

• Ensure documentation specifies a confirmed diagnosis of plasminogen deficiency, not just suspected or rule-out.
• Do not confuse this with other coagulation factor deficiencies; this code is specific to plasminogen.
• Code any associated manifestations, such as ligneous conjunctivitis (H10.811-H10.819) or other specific organ involvement, as secondary diagnoses.