Essential fructosuria

This code describes a benign, inherited metabolic disorder characterized by the inability to metabolize fructose due to a deficiency in hepatic fructokinase. Individuals with this condition excrete unmetabolized fructose in their urine, but typically remain asymptomatic and do not experience adverse health effects from fructose consumption.

Assign this code when documentation confirms a diagnosis of essential fructosuria, often identified through urine tests showing fructosuria in an otherwise healthy individual. This diagnosis is typically made after ruling out more severe fructose metabolism disorders.

• Do not confuse with hereditary fructose intolerance (E74.10) or fructose-1,6-bisphosphatase deficiency (E74.19), which are more severe conditions.
• This is a lifelong condition, so it may be reported on subsequent encounters if relevant to the patient's care.
• Documentation should clearly state "essential fructosuria" or indicate a benign, asymptomatic fructosuria.