E28.39
ICD-10-CMThis code signifies a condition where the ovaries cease to function normally before the age of 40, leading to irregular or absent menstrual periods and infertility. It represents ovarian dysfunction not due to menopause or surgical removal, but rather an intrinsic failure of the ovaries themselves.
Use this code when documentation indicates premature ovarian insufficiency (POI) or premature ovarian failure (POF) that is not specified as autoimmune, iatrogenic, or due to other known causes. This diagnosis is supported by clinical findings of amenorrhea or oligomenorrhea, elevated gonadotropin levels (FSH, LH), and low estrogen levels in women under 40.
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