Other drug-induced agranulocytosis

This code signifies a severe and potentially life-threatening reduction in granulocytes (a type of white blood cell) caused by an adverse reaction to a medication. It represents a drug-induced bone marrow suppression leading to a compromised immune system.

Assign this code when documentation clearly indicates agranulocytosis as a direct consequence of drug therapy, and the specific drug is not otherwise specified or is a drug other than antineoplastic agents. Supporting documentation should include laboratory findings showing a significant decrease in granulocyte count and a confirmed causal link to a prescribed or illicit drug.

• Always identify the specific drug causing the agranulocytosis, if known, and code it as an adverse effect (T36-T50 with a 5th or 6th character of 5).
• Distinguish from agranulocytosis due to antineoplastic chemotherapy (D70.1) or other specified causes.
• Ensure physician documentation explicitly states "drug-induced" and identifies the causative agent for accurate coding.