Refractory cytopenia with multilineage dysplasia

This code signifies a myelodysplastic syndrome (MDS) characterized by persistent low blood cell counts (cytopenia) affecting two or more cell lines (red blood cells, white blood cells, or platelets) despite appropriate treatment. Bone marrow examination reveals abnormal development (dysplasia) in these multiple cell lines.

Apply this code when documentation explicitly states a diagnosis of "refractory cytopenia with multilineage dysplasia" or "RCMD." This diagnosis is typically established after bone marrow biopsy and cytogenetic analysis, confirming the specific subtype of MDS.

• Ensure the documentation clearly specifies "multilineage dysplasia" and "refractory" to differentiate from other MDS subtypes.
• Do not confuse with other MDS codes that specify single-lineage dysplasia or excess blasts.
• Sequence this code as the primary diagnosis when it is the reason for the encounter.