Anaplstc lg cell lymph, ALK-pos, extrnod and solid org sites

This code signifies a rare and aggressive form of non-Hodgkin lymphoma characterized by the presence of anaplastic lymphoma kinase (ALK) protein and its occurrence in tissues outside of the lymph nodes, such as skin, bone, or soft tissue. It involves the proliferation of large, pleomorphic lymphocytes with distinctive immunophenotypic features.

Assign this code when documentation explicitly states a diagnosis of anaplastic large cell lymphoma that is confirmed to be ALK-positive and originates or primarily affects extranodal or solid organ sites. Supporting documentation should include pathology reports confirming ALK positivity and the specific extranodal location.

• Ensure pathology reports clearly identify ALK-positive status; do not assume based on morphology alone.
• Distinguish from ALK-negative anaplastic large cell lymphoma, which codes to a different category.
• Specify the exact extranodal site with an additional code if known and clinically relevant.