Diffuse large B-cell lymphoma, unspecified site

This code signifies a diagnosis of diffuse large B-cell lymphoma (DLBCL), a fast-growing type of non-Hodgkin lymphoma, without specifying the primary anatomical location of the disease. DLBCL originates from B-lymphocytes and can occur in lymph nodes or extranodal sites.

Use this code when the medical record clearly documents a diagnosis of diffuse large B-cell lymphoma, but the specific site of origin or primary involvement is not identified or is unknown at the time of coding. This is often applicable during initial diagnosis or when pathology reports confirm DLBCL without further site specification.

• Do not use this code if a specific anatomical site for the DLBCL is documented; instead, use the more specific C83.3- subcategory codes.
• Always review pathology reports and physician notes for any mention of the primary site to ensure the most specific code is selected.
• Consider sequencing this code as the primary diagnosis when it represents the reason for the encounter or admission.