Malignant neoplasm of endometrium

This code signifies a primary cancerous tumor originating in the lining of the uterus, known as the endometrium. It specifically refers to malignant neoplasms, indicating invasive or potentially invasive cellular growth within this tissue.

Apply this code when documentation confirms a diagnosis of endometrial cancer. This is typically supported by pathology reports following biopsy or surgical resection, or by imaging studies and clinical assessment indicating a primary malignant lesion of the endometrium.

• Ensure documentation specifies the endometrium as the primary site; do not use for secondary or metastatic lesions to the endometrium.
• Distinguish from other uterine malignancies (e.g., C54.0 for isthmus, C54.2 for myometrium) based on documented tumor origin.
• Always sequence this code as the primary diagnosis when it is the reason for the encounter, unless another condition is explicitly identified as the principal diagnosis.