Kaposi's sarcoma of soft tissue

This code represents a malignant neoplasm characterized by the proliferation of endothelial cells, specifically affecting the soft tissues of the body. Kaposi's sarcoma presents as skin lesions, but this code is for involvement of subcutaneous tissue, fascia, muscle, or other connective tissues.

Assign this code when documentation specifies Kaposi's sarcoma involving soft tissue sites, such as subcutaneous tissue, muscle, or other connective tissues, excluding visceral organs. This code is appropriate when the physician explicitly diagnoses Kaposi's sarcoma of soft tissue, often in patients with compromised immune systems.

• Differentiate from cutaneous Kaposi's sarcoma (C46.0) and Kaposi's sarcoma of lymph glands/nodes (C46.3).
• Always review pathology reports and physician notes for precise anatomical site documentation.
• Code any associated HIV infection (B20) as a secondary diagnosis when applicable.