A51.49
ICD-10-CMThis code represents various manifestations of secondary syphilis that are not specifically classified elsewhere. These conditions arise during the secondary stage of syphilis infection, typically characterized by widespread systemic symptoms following the primary chancre. Examples include syphilitic hepatitis, nephritis, or osteitis occurring during this stage.
Use this code when documentation clearly indicates a secondary syphilitic condition that is not a specific skin, mucous membrane, or ocular manifestation. This code is appropriate when the physician explicitly diagnoses a "secondary syphilis with [other organ involvement]" where a more specific code for that organ involvement in secondary syphilis is unavailable. Documentation should specify the secondary stage of syphilis and the affected organ or system.
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