A51.46
ICD-10-CMThis diagnosis code signifies bone involvement as a manifestation of the secondary stage of syphilis. It indicates an inflammatory process affecting the skeletal system due to disseminated treponemal infection. Patients may present with bone pain, swelling, or periostitis.
Assign this code when documentation explicitly states secondary syphilis with osteopathy or bone lesions attributable to the infection. Supporting documentation should include a positive syphilis serology (e.g., RPR, VDRL, FTA-ABS) and imaging findings (e.g., X-ray, MRI) consistent with osteopathy in the context of secondary syphilis.
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